A Longitudinal Study to Determine the Effect of Gene-based Personalised Diet and Physical Activity Advice on Adiposity Indices in University Students
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 400
- 主要终点
- Body weight in kg
研究概览
简要总结
A longitudinal study to determine the effect of gene-based personalised diet and physical activity advice on adiposity indices in university students.
详细描述
The study uses a randomised controlled design; data for all variables (participant characteristics, height, weight, body mass index (BMI), waist circumference (WC), body fat percentage (BF%), healthy eating motivation, dietary intake and physical activity) will be collected initially from participants at St Mary's University during September and October 2019. Participants will be genotyped, stratified randomisation (based on genotype and BMI) will be used to allocate participants to three different groups (1. Control: no advice, 2. Non genetic personalised advice: dietary and physical activity advice based on reported dietary intake and physical activity 3. Genotype- based personalised advice: dietary and physical activity advice based on genotype, reported dietary intake and physical activity. Following allocation to groups participants in groups 2 and 3 will receive appropriate dietary and physical activity advice via email (appendix a) and all participants will complete the healthy eating motivation questionnaire for a second time. In April/May 2020 follow up variables (smoking status, weight, BMI, WC, BF%, healthy eating motivation, dietary intake and physical activity) will be measured again. These follow up variables will be measured every September and April/May until September 2022. After each follow up participants in groups 2 and 3 will be resent their dietary and physical activity advice and updated information based on their reported dietary intake and physical activity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 25 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-25 years
排除标准
- •Pregnancy and lactation
- •Chronic disease
- •A history of disordered eating and following a restricted diet.
研究组 & 干预措施
Genotype- based personalised advice
dietary and physical activity advice based on genotype, reported dietary intake and physical activity
干预措施: Genotype- based personalised advice (Genetic)
Genotype- based personalised advice
dietary and physical activity advice based on genotype, reported dietary intake and physical activity
干预措施: Non genetic personalised advice (Behavioral)
Control
no advice
Non genetic personalised advice
dietary and physical activity advice based on reported dietary intake and physical activity
干预措施: Non genetic personalised advice (Behavioral)
结局指标
主要结局
Body weight in kg
时间窗: 3 years
Weight will be measured to the nearest 0.1 kg
Body fat percentage
时间窗: 3 years
Body fat percentage will be measured to the nearest 0.1%
Body mass index in Kg/m2
时间窗: 3 years
calculated from measured height and weight
次要结局
- Dietary intake(3 years)
- Physical activity(3 years)
- Participants motivation to eat healthily(3 years)
