A Prospective, Randomized, Clinically Based Study on the Response to Selective Laser Trabeculoplasty Versus Argon Laser Trabeculoplasty in Patients Who Are Under 60 Years of Age
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Intraocular pressure
研究概览
简要总结
Laser trabeculoplasty is a routine treatment for glaucoma and can be performed with either argon (ALT) or selective Yag (SLT) lasers. The effectiveness of each has not been studied in patients under 60 years, which is younger than average for the procedure. The study hypothesis is that there will be no difference between the two laser types.
详细描述
Forty-two young patients (age 29 to 60) had one eye randomized to ALT (n = 22) or SLT (n = 20). Intraocular pressure was measured prior to laser and 1 hour, 1 day, 6 weeks, 3 months, every 3 months until 2 years, and then yearly post-laser. χ2 analysis and student's t-test were used to determine statistical significance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age < 60 years
- •Intraocular pressure not adequately controlled
排除标准
- •Prior laser treatment
研究组 & 干预措施
Argon laser trabeculoplasty
Patients received standard argon laser treatment
干预措施: Argon laser trabeculoplasty (Procedure)
Selective laser trabeculoplasty
Patients received a standard selective laser treatment
干预措施: Selective laser trabeculoplasty (Procedure)
结局指标
主要结局
Intraocular pressure
时间窗: Two years
The intraocular pressure was measured at 6 weeks, 4.5 months, 9, 12, 18 and 24 months following the laser treatment.
次要结局
未报告次要终点
研究者
Dr. Catherine Birt
MD
Sunnybrook Health Sciences Centre