EUCTR2016-002086-54-NL进行中（未招募）1 期
A randomized trial of the effect of antiplatelet therapy (Aspirin, Aspirin and Clopidogrel or Ticagrelor) on the occurrence of atherothrombotic and cardiovascular adverse events following lower extremity perctaneous transluminal angioplasty. - ASCOT
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 1,806
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •All symptomatic patients ver 18 years of age with non-acute peripheral artery disease are eligible for inclusion if there is a need for percutaneous endovascular intervention.
- •(1) lesions of the iliac, femoropopliteal and below the knee (BTK) arteries; (2) eligibility of lesions for PTA or recanalization with or without additional stenting (ST), (3) all TASC lesions; (4) all Rutherford (1-6) classes
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 400
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 1400
排除标准
- •Exclusion criteria are acute ischemia, PAD due to aneurysm abdominal or popliteal, patients with reported intolerance or hypersensitivity for the study medications, impossibility of discontinuing current antiplatelet therapy, the use of anticoagulant therapy (coumarin derivatives; acenocoumarol /fenprocoumon /warfarin), the use of non-steroidal anti-inflammatory drugs in the two weeks prior to the venepuncture to determine eventual aspirin resistance, a history of platelet/bleeding abnormalities, a platelet count < 100x*10^6/dl and patients with a life expectancy less than one year. known CYP2C19 polymorphism.
研究者
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