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临床试验/NL-OMON50606
NL-OMON50606招募中不适用

Assessment of cardiovascular risk in patients with severe obstructive sleep apnea syndrome - CRIOS

Academisch Medisch Centrum0 个研究点目标入组 50 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
50

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • 1. Age >50 years
  • 2. AHI>30 or AHI <15 depending on group
  • 3. Symptoms matching the diagnosis of OSAS for at least 6 months
  • 4. OSAS as diagnosed by polysomnography

排除标准

  • 1. Malignant diseases or any clinically significant medical condition that
  • could interfere with the conduct of the study in the opinion of the
  • investigator.
  • 2. Chronic or recent (<1 month) infections and/or clinical signs of acute
  • infection and/or CRP >10 mg/L
  • 3. Auto-immune diseases
  • 4. Recent or chronic immunosuppressant or antibiotic usage
  • 5. Type I or II diabetes mellitus
  • 6. Smoking or alcohol abuse
  • 7. Sleeping disorder other than OSAS
  • 8. Standard contra-indications to 18F-FDG PET, and CT based on physicians
  • experience and current practices
  • 9. Exposure to radiation in a different study
  • 10. History of MI/Stroke or known coronary artery diseas
  • 11. BMI >40 kg/m2
  • 12. Weight above 190kg, diameter >69cm (limits CT scanner)

研究者

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