Genetic Disorders of Obesity Program Database
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- Prevalence of genetic causes of severe, early-onset obesity
研究概览
简要总结
This study collects data on children with severe, early-onset obesity.
详细描述
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children are asked to participate in a prospective, observational study. The investigators collect demographic information, body measurements, medical/family history, as well as other questionnaires. Additionally, genetic information, medical lab results, and responses to treatment options are collected. The goal of the study is to determine if the investigators can better understand which children would benefit from testing and further workup as well as to understand how obesity develops in these children and adolescents.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For individuals 2 years and older, BMI > 97 percentile
- •For individuals < 2 years old, weight-to-length ratio > 95th percentile
排除标准
- •No other exclusion criteria
结局指标
主要结局
Prevalence of genetic causes of severe, early-onset obesity
时间窗: through study completion, an average of 10 years
We will measure the number of genetic variants identified in clinical testing
次要结局
- Change in BMI over time(through participant completion, an average of 2 years)
研究者
Stephanie Sisley
Associate Professor
Baylor College of Medicine