ACTRN12620000676910尚未招募1 期
Allogeneic Amniotic Epithelial Cells for the Treatment of COVID-19 related respiratory failure, a pilot feasibility randomised controlled trial
适应症
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 85 Years（—）
- 性别
- All
入选标准
- •Patients included in this study must satisfy ALL of the following criteria:
- •Proven or highly suspected COVID-19 through a polymerase chain reaction (PCR) test of a nasal swab; or a negative PCR test with typical radiological finding or CT scan in the absence of alternate diagnoses; or patients with respiratory failure of infective origin admitted to ICU during the COVID-19 pandemic
- •Receiving supplemental oxygen, due to respiratory failure, with PaO2/FiO2 ratio less than or equal to 200 (moderate to severe) or an SaO2 < 92% while receiving more than or equal to 4 litres of O2 via face mask.
排除标准
- •Patients will be excluded if they have ANY of the following:
- •Less than 18 years old
- •Have been intubated for more than 48 hours,
- •Documented significant chronic obstructive airway disease
- •Death is imminent and inevitable within 24 hours,
- •Limitation of therapy includes no invasive mechanical ventilation,
- •Severe global left ventricular dysfunction with an ejection fraction of <25%,
- •Receiving extracorporeal support or is highly likely within the next 12 hours,
- •Acute fulminant hepatitis
研究者
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