Health Status, Quality of Life and Function in Survivors After Radical Treatment for Prostate Cancer. A Cross-sectional Study Focusing on Older Survivors. Part IIB
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 109
- 试验地点
- 1
- 主要终点
- Physical performance
研究概览
简要总结
The present study is the last part of a larger project investigating the health, quality of life and function of men having received radical treatment for prostate cancer in 2014-2018. In this study, physical function and level of physical activity will be tested and registered in a selection of older men who participated in the foregoing parts of the project. Comparisons will be made to similar data from a population-based cohort, matched on age and education.
详细描述
Background:
Prostate cancer is the most common cancer among Norwegian men with about 5000 new cases each year. Median age at diagnosis is 70 years. Radical treatment for local or locally advanced prostate cancer is either radiotherapy or surgery. Older men more frequently have an aggressive cancer compared to younger men. Despite this, increasing age seems to be a major determinant for omitting curative treatment. Reasons may be worries about side effects in a more vulnerable population, and scarce knowledge about the long-term impact of radical treatment on the older patients' health, function, and quality of life.
Design:
The study is the last part of larger project investigating the health status, quality of life, and function among survivors after radical prostate cancer treatment, focusing on older survivors in particular (NCT04863352). In this study, physical function, physical activity, quality of life, and cardiopulmonary fitness will be evaluated in a subgroup of those men who participated in the foregoing parts of the overarching project, and who were 70 years or more when they received their treatment. The study has a cross-sectional design, and for comparison with a general population, existing data from male participants in the fourth wave of the Trøndelag Health Survey (HUNT4) will be used. The control group will be matched with the study group on age and education, with a distribution 1:3 (cancer survivors : controls).
Aims:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •survivors with clinically significant relapse (verified metastases/local progression and/or start of lifelong antiandrogen therapy)
结局指标
主要结局
Physical performance
时间窗: Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer
Physical performance as measured by the short physical performance battery (SPPB)
次要结局
- Sedentary activity(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- one legged balance test(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- Physical activity(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- Grip strength(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- cardiorespiratory fitness (CRF)(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- physical function(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- global quality of life(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)
- self-reported physical activity(Cross-sectional study, assessment 3 to 7 years afte radical treatment for prostate cancer)