跳至主要内容
临床试验/CTRI/2025/06/088031
CTRI/2025/06/088031尚未招募4 期

Comparison of analgesic efficacy of Serratus Posterior Superior Intercostal Plane Block with Pectoralis nerve block (PEC II) in patients undergoing Modified radical mastectomy: A Randomized control trial.

All India Institute of Medical Sciences, Patna1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2025年6月18日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
64
试验地点
1
主要终点
Requirement of post operative opiod (total dose of Morphine) in 24 hours.

研究概览

简要总结

Postoperative pain is asignificant concern following Modified Radical Mastectomy (MRM). Pain after MRMnot only causes a strong stress reaction and adverse emotionalexperience but also affects postoperative rehabilitation. Hence, differentanalgesia techniques, including local anaesthetic infiltration, intercostalnerve block, paravertebral block, Serratus anterior plane block and thoracicepidural anaesthesia, have been described to attenuate the intensity of acutepostoperative pain. Paraspinal block and thoracic epidural anaesthesia maycause parasympathetic symptoms, resulting in hypotension and bradycardia. Additionally, they could lead to general spinalanaesthesia, local hematoma, infection, anaesthetic poisoning, and paraspinalmuscle pain. Serratus anterior plane block only providesanterolateral hemi thoracic analgesia and Paravertebral block is associatedwith a high risk of complications such as pneumothorax and vascular injury. Serratusposterior superior intercostal plane block is a novel block that provideanteroposterior thoracic analgesia. Ultrasound guided Pectoral nerve block (PECII) has been the most popular block after breast surgeries because of its easeof administration and safety. Thisrandomized controlled trial aims to compare the analgesic efficacy of Serratusposterior superior block with Pectoral nerve block (PEC II).

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 75.00 Year(s)(—)
性别
Female

入选标准

  • ASA 1 and 2 patients scheduled for Modified Radical Mastectomy.

排除标准

  • 1 Patient refusal to participate in the study 2 BMI more than 40 3 Skin lesions or infection at the planned site of needle insertion 4 Inability to understand about the PCA pump.

结局指标

主要结局

Requirement of post operative opiod (total dose of Morphine) in 24 hours.

时间窗: 24 hours.

次要结局

  • 1 Intraoperative opioid (Fentanyl) consumption.(2 Time of first rescue analgesic administration.)

研究者

发起方
All India Institute of Medical Sciences, Patna
申办方类型
Government medical college

研究点 (1)

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