fMRI analysis of the visual cortex in neovascular Age-related Macular Degeneration

Medizinische Universität Wien, Universitätsklinik für Augenheilkunde0 个研究点目标入组 41 人开始时间: 2013年11月19日最近更新: 2019年4月30日

适应症

试验速览

暂无简介。

•Patients 50 years of age or older
•ability to read
•mastering the German language
•signing the informed consent
•(for patients): new onset, treatment naive sub-or juxtafoveal choroidal neovascularization caused by AMD
•(for patients) Visual Acuity of 20/400-20/40
•(for healthy controls): Visual Acuity of 20/16- 20/30
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 20
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 20

•(for patients): Any prior initial intravitreal treatment or previous laser treatment
•(for healthy controls): presence of any retinal and/or optic nerve disease
•History of uncontrolled glaucoma in the study eye (defined as intraocular pressure = 25 mmHg despite treatment with anti-glaucoma mediation).
•Aphakia or absence of the posterior capsule in the study eye.
•Cataract > grade 2 (according to lens opacities system)
•Amblyopia
•Active intraocular inflammation (grade trace or above) in the study eye
•All exclusion criteria that apply to MRI scans: Pacemaker, metal debris, metalliferous coil, claustrophobia
•Pregnancy

发起方

Medizinische Universität Wien, Universitätsklinik für Augenheilkunde