跳至主要内容
临床试验/NCT07359313
NCT07359313尚未招募不适用

Incidence of Colon Ischemia in Patients After Cardiopulmonary Resuscitation (CPR): a Prospective Single-center Epidemiological Incidence Study

University Hospital Freiburg0 个研究点目标入组 200 人开始时间: 2026年1月7日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
200

研究概览

简要总结

Bedside colonoscopy 24-36 hours after successful CPR

详细描述

According to previous observations, many patients after CPR develop acute non-occlusive mesenteric ischemia. However, due to the lack of established screening strategies, the number of unreported cases may be high. Routine colonoscopy at 24-36 hours after CPR may be a safe, easy and cost-effective strategy for early detection of severe mesenteric ischemia and transfer to surgical treatment. However, this strategy has not been formally evaluated in larger prospective cohorts. In our center, we perform routine colonoscopy at 24 to 36 hours after cardiac arrest in all patients who receive extracorporeal CPR (ECPR), i.e., in all patients with prolonged cardiac arrest refractory to conventional CPR measures who therefore receive venoarterial extracorporeal membrane oxygenation (VA ECMO) for cardiocirculatory support. In these patients, colonoscopy screening was feasible and safe, and our data suggest clinical benefit.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients (≥ 18 years) admitted to the participating department AND
  • in-hospital or out-of-hospital cardiac arrest (IHCA, OHCA)

排除标准

  • resuscitation period of ≤ 5 minutes
  • awake and contactable patients (GCS ≥ 13)

研究者

发起方
University Hospital Freiburg
申办方类型
Other
责任方
Principal Investigator
主要研究者

PD Dr. Alexander Supady

Senior Physician

University Hospital Freiburg

相似试验