Impact of a Low Carbohydrate Breakfast on Glucose Control in Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 2
- 主要终点
- Incremental area under the glucose curve (continuous glucose monitor)
研究概览
简要总结
Large glucose excursions at breakfast are prevalent in type 2 diabetes and can contribute to sustained hyperglycaemia across the day. Lowering consumption of dietary carbohydrate is known to reduce post-meal glucose excursions but it is unknown whether lowering the carbohydrate at breakfast only will impact subsequent post meal glucose excursions throughout the day. The aim of this study is to examine, under free living conditions and using typical dietary patterns, whether eating a breakfast low in carbohydrate can lower daily post-meal glycemia when compared to consuming a low-fat breakfast (per the current diabetes guidelines).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Physician-diagnosed Type 2 Diabetes (>6 months)
排除标准
- •Exogenous Insulin
- •A1c > 9%
- •Cardiovascular, liver, or renal other disease
- •Breakfast and meal skippers
研究组 & 干预措施
Low Carbohydrate Breakfast
Breakfast composition containing <10% carbohydrate, 75% fat, 15% protein Matched calories
干预措施: Low Carbohydrate Breakfast (Behavioral)
Low Carbohydrate Breakfast
Breakfast composition containing <10% carbohydrate, 75% fat, 15% protein Matched calories
干预措施: Guidelines Breakfast (Behavioral)
Guidelines Breakfast
Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories
干预措施: Low Carbohydrate Breakfast (Behavioral)
Guidelines Breakfast
Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories
干预措施: Guidelines Breakfast (Behavioral)
结局指标
主要结局
Incremental area under the glucose curve (continuous glucose monitor)
时间窗: 24 hour (one day)
次要结局
- Mean Blod Glucose (continuous glucose monitor)(24 hours (one day))
研究者
Jonathan Little
Dr Jonathan P Little
University of British Columbia
