Evaluation the comparative efficacy of homoeopathic mucolytic in chronic bronchitis: a randomized trial of senega officinalis, silphium, ammoniacum gummi and balsamum peruvianum using cat criteria
试验速览
- 阶段
- 1/2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To evaluate the highest mucolytic effect of any one medicine from all of four medicine taken in study - Senega Officinalis, Silphium, Ammoniacum Gummi and Balsam Peruvianum in cases of chronic bronchitis along with their comparative analysis.
研究概览
简要总结
Chronic bronchitis one of the disorders under chronic obstructive pulmonary disease (COPD), which is frequently linked to prolonged exposure to irritants like cigarette smoke, air pollution, or work-related dangers. Chronic bronchitis, an inflammation of the airways, characterized by a persistent productive cough and expectoration that lasts for two consecutive years and at least three months out of the year, is a common respiratory condition affecting individuals in their middle to later years. Mucus-secreting glands and goblet cells hyper-proliferate as a result of this inflammation, which results in increasedmucus production and impeded mucociliary clearance. Sputum production, breathing difficulties, and a persistent productive cough are the outcome, and they get worse with time. It is traditionally managed with conventional therapies such as bronchodilators, mucolytics and corticosteroids. With medicinal management it is necessary to stop smoking and avoid irritants. Along with these oxygen therapy, vaccination, pulmonary rehabilitation and antibiotics are also required occasionally.
Despite the availability of various treatments, many remain dissatisfied with conventional therapies, and there is a growing interest in exploring alternative options. Homoeopathic remedies such as Senega Officinalis, Silphium, Ammoniacum Gummi, and Balsam Peruvianum offer alternative approaches to managing chronic bronchitis as mucolytics. By evaluating their mucolytic efficacy, this research aims to provide new insights and treatment options for chronic bronchitis, potentially influencing clinical practice and expanding the understanding of these less-utilized remedies.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •• Individual with diagnostic symptoms of chronic bronchitis • Age group between 40-70 years • Patient of both sexes • Patient from all socio economical status • Patient who are willing for chest x ray investigation (before-after treatment).
排除标准
- •• Patient with severe respiratory function impairment • Patient with any malignant disease • Patient with severe comorbidities • Patient with autoimmune disorders • Patient present with most similimum medicine indication other then taken medicine for this synopsis.
结局指标
主要结局
To evaluate the highest mucolytic effect of any one medicine from all of four medicine taken in study - Senega Officinalis, Silphium, Ammoniacum Gummi and Balsam Peruvianum in cases of chronic bronchitis along with their comparative analysis.
时间窗: 12 months , per patient 2 months
次要结局
- to assess the impact of these remedies on patients quality of life and respiratory function.(12 months per patient 2 months)
研究者
Dr Dhara Patel
Parul institute of homoeopathy and research, Parul University, Post Limda, Waghodia, Vadodara
