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临床试验/NCT04936165
NCT04936165Unknown不适用

Circulation and Oxygenation Changes of Deep Tissue Respond on Low Level Light/Laser Therapy (LLLT) in the Healthy Population

Ting Li1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2021年6月25日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
40
试验地点
1
主要终点
Δ[HbO2]

研究概览

简要总结

This study aims to investigate the circulation and oxygenation changes of deep tissue respond on low level light/laser therapy (LLLT) in the healthy population. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to noninvasively monitor hemodynamic indicators of brain and forearm muscle groups, including total hemoglobin ([tHb]), and blood flow (BF) and oxygen consumption (VO2).

详细描述

Low level light/laser therapy (LLLT) employs visible or near-infrared light generated from a laser or light emitting diode (LED) system. It has beneficial effects on a wide range of disease, including improving wound healing, reducing pain, improving memory, treat cancer, and many other human applications. This study aims to investigate the circulation and oxygenation changes of deep tissue respond on low level light/laser therapy (LLLT) in the healthy population. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to noninvasively monitor hemodynamic indicators of brain and forearm muscle groups, including total hemoglobin ([tHb]), and blood flow (BF) and oxygen consumption (VO2). Then the investigators concluded the effect of LLLT, according to compare the difference between the experimental group and control group.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy participants with no strenuous exercise or alcohol consumption prior to the test

排除标准

  • having risk factors associated with cardiovascular disease

结局指标

主要结局

Δ[HbO2]

时间窗: through study completion, an average of 1 year

changes of oxyhemoglobin concentration

Δ[Hb]

时间窗: through study completion, an average of 1 year

changes of deoxy-hemoglobin concentration

Δ[tHb]

时间窗: through study completion, an average of 1 year

changes of total hemoglobin concentration

次要结局

  • Subcutaneous fat thickness(through study completion, an average of 1 year)

研究者

发起方
Ting Li
申办方类型
Unknown
责任方
Sponsor Investigator
主要研究者

Ting Li

Full professor

Chinese Academy of Medical Sciences

研究点 (1)

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