Mayo Clinic Precure - Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- Mayo Clinic
- 入组人数
- 100,000
- 试验地点
- 1
- 主要终点
- Build a comprehensive, multi-omics and phenotype dataset
研究概览
简要总结
The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease advancement before it becomes serious or complex, and 4) identify potential targets for disease therapy.
Participants will be asked to:
- collect biological samples,
- download a mobile app,
- collect speech (voice) recordings, and
- complete surveys
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years
- •Registered Mayo Clinic patient
- •Able to provide informed written consent
- •Able to receive mail and packages within a United States (US) state
- •Able to collect and ship samples within a US state via FedEx for overnight delivery
排除标准
- •Active hematological cancer or history of a hematological cancer
- •Allogeneic Bone Marrow Transplant (autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
- •Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study (e.g., reduced ability to comprehend, i.e., dementia, intellectual disability, etc.)
研究组 & 干预措施
Suspected Genetic Predisposition or Multi-Omics Contribution
Patients with a diagnosis or phenotype with the potential for association with a genetic predisposition or Multi-Omics Contribution
Health Control
Patients with no diagnosis associated with a genetic predisposition or Multi-Omics Contribution.
结局指标
主要结局
Build a comprehensive, multi-omics and phenotype dataset
时间窗: Up to 5 years
次要结局
未报告次要终点
研究者
Konstantinos N. Lazaridis, M.D.
Executive Director, Center for Individualized Medicine
Mayo Clinic