Comparison between the efficacy of fentanyl and paracetamol-magnesium combination in attenuating hemodynamic response to sternotomy in patients undergoing coronary artery bypass grafting-a randomized control trial

Kovai medical center and hospital1 个研究点分布在 1 个国家目标入组 90 人开始时间: 2023年5月15日最近更新: 2023年3月5日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 90
试验地点: 1
主要终点: To compare the effects of fentanyl and paracetamol-magnesium combination in attenuating increase in BP and heart rate in patients undergoing Coronary artery bypass grafting

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study is a randomized, double-blind, parallel group, single centre trial comparing the efficacy of fentanyl 2mcg/ kg and paracetamol 1gm-magnesium 1gm combination in attenuating increase in BP and heart rate as a response to sternotomy in patients undergoing elective Coronary artery bypass grafting. This study also aims to compare the time taken for extubation,postoperative pain intensity and analgesia requirements in first 24 hours of postoperative period.

研究设计

研究类型: Interventional
分配方式: Other
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 35.00 Year(s) 至 70.00 Year(s)（—）
性别: All

入选标准

•ejection fraction>50% ASA grade 3 and 4.

排除标准

•1.patients who are not willing 2.severe left ventricular dysfunction 3.patients who are on ionotropes 4.patients on IABP 5.patients with conduction blocks 6.patients requiring valvular replacements.

结局指标

主要结局

To compare the effects of fentanyl and paracetamol-magnesium combination in attenuating increase in BP and heart rate in patients undergoing Coronary artery bypass grafting

时间窗: From the time of induction to 5 minutes following sternotomy

次要结局

To compare the time to extubation, postoperative pain intensity and analgesia requirements(First 24 hours of postoperative period)

研究者

发起方

Kovai medical center and hospital

申办方类型

Private hospital/clinic

研究点 (1)

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