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临床试验/NCT07508163
NCT07508163尚未招募不适用

Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders: Evidence From Lateral Ankle Sprain and Patellofemoral Pain Syndrome

Cairo University0 个研究点目标入组 90 人开始时间: 2026年3月30日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
90
主要终点
APSI

研究概览

简要总结

Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability. However, the direction-specific nature of balance deficits and comparative patterns across these conditions remain unclear. Therefore, the aim of this study is to compare overall, mediolateral, and anteroposterior postural stability indices among individuals with LAS, PFPS, and healthy controls using the Biodex Balance System

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
20 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Inclusion criteria for the lateral ankle sprain group will include participants with a clinically confirmed history of unilateral lateral ankle sprain, who are at least three months post-injury to avoid acute inflammatory effects, and who report residual symptoms such as pain or functional limitation. Participants in the patellofemoral pain syndrome group will have a clinical diagnosis of patellofemoral pain syndrome characterized by anterior or retropatellar knee pain aggravated by functional activities such as stair climbing, squatting, or prolonged sitting, with symptoms persisting for at least three months. Healthy control participants will have no history of lower limb musculoskeletal injury, pain, or functional impairment within the past three months and will be matched to the patient groups based on age and sex. All participants across groups will be able to stand independently without assistive devices and will demonstrate sufficient cognitive ability to understand and follow study instructions

排除标准

  • Exclusion criteria for all groups will include a history of lower limb fracture or surgery, neurological or vestibular disorders that may affect balance or postural control, uncorrected visual impairments, systemic inflammatory or rheumatological diseases, and metabolic or neurological conditions known to influence neuromuscular performance. Participants currently engaged in structured balance, proprioceptive, or neuromuscular training programs, as well as those taking medications that may affect balance or postural stability, will also be excluded from the study.

研究组 & 干预措施

group of lateral ankle sprain (LAS)

30 patients with LAS of both sexes with ages from 20 to 30 years

干预措施: diagnosis of APSI, MLSI, OASI (Diagnostic Test)

group of patellofemoral pain syndrome (PFPS)

30 patients with PFPS of both sexes with ages from 20 to 30 years

干预措施: diagnosis of APSI, MLSI, OASI (Diagnostic Test)

healthy control group

30 healthy matched participants of both sexes with ages from 20 to 30 years

干预措施: diagnosis of APSI, MLSI, OASI (Diagnostic Test)

结局指标

主要结局

APSI

时间窗: one shot assessment within one week

anterior-posterior stability index

MLSI

时间窗: one shot assessment within one week

Medial-lateral stability index

OASI

时间窗: one shot assessment within one week

overall stability index

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Azza Mohammed

professor

Cairo University

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