NCT04320927Unknown不适用
Iatrogenic Withdrawal Symptoms in Severe Traumatic Brain Injury
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 215
- 试验地点
- 1
- 主要终点
- proportion of patients with positive IWS diagnosis
研究概览
简要总结
Iatrogenic withdrawal symptomes has been associated with prolonged mechanical ventilation and the and the derived symptoms such as fever and agitation has been shown to cause significantly prolonged ICU and hospital length of stay. The incidence of IWS in the adult general ICU ranges from 16,7-55%. To this date, the incidence of IWS has not been studied in patients with TBI.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients suffering from severe TBI and were mechanical ventilated and received continuous infusions of opioids, benzodiazepines and neuromuscular blocking agents for 72ours or more
排除标准
- •age <18 years, patients who died before discharge, chronic alcohol abuse, regular use of heroin, cocaine and amphetamines, chronic use of opioids, patient that were primary admitted to other ICUs and patients that were moved to other ICUs with ongoing infusions.
结局指标
主要结局
proportion of patients with positive IWS diagnosis
时间窗: 20-6-2019
次要结局
未报告次要终点
研究者
Markus Harboe Olsen
md
Rigshospitalet, Denmark
研究点 (1)
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