NL-OMON37385已完成不适用
The role of humoral autoimmunity in the aetiology of achalasia. - Antibodies in achalasia.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients with achalasia:
- •- Diagnosis of achalasia confirmed by:
- •- Oesophageal manometry; aperistalsis, LOS dysrelaxation and hypertensive LOS (>10mmHg).
- •- Barium oesophagogram; delayed emptying, aperistalsis and dilatation of the oesophagus with narrowing of the distal oesophagus.
- •- Eckhardt score * 2.
- •- Age 18-75 years.
- •- Written informed consent;Healthy controls:
- •- Age 18-75 years.
- •- Written informed consent
排除标准
- •Patients with achalasia:
- •- Pseudoachalasia
- •- Chagas disease
- •- Upper gastrointestinal malignancy;Healthy controls:
- •- Symptoms suggestive of oesophageal disease.
- •- History of malignancy.
- •- History of diseases affecting the upper gastrointestinal tract (gastro-oesophageal reflux disease, eosinophilic oesophagitis)
- •- Pseudoachalasia
- •- Chagas disease
- •- Autoimmune diseases
研究者
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