Prevalence and clinical impact of Human Papilloma Virus in patients with Head and Neck Squamous Cell Cancer treated prospectively at Prince Aly Khan Hospital - nil

Prince Aly Khan Hospital0 个研究点目标入组 300 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1.Pathologically (histologically or cytologically) proven AJCC/TNM staged diagnosis of squamous cell carcinoma of the oral cavity, oropharynx, larynx, or hypopharynx (excluding lip, nasopharynx, or sinuses)
•2.Zubrod Performance Status 0-1
•3.Age 18years and above
•4Patient must sign a study-specific informed consent prior to study entry, which includes mandatory submission of tissue for HPV analysis

•1.Evidence of distant metastases or simultaneous primaries
•2.Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 3 years with the exception of cervical carcinoma in situ and adequately treated basal cell or squamous cell carcinoma of the skin or untreated/treated low-risk prostate cancer(defined as clinical or pathologic T1c, N0 M0, PSA 10, Gleason 7, 50% of the total cores positive for cancer);
•3.Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a different cancer is allowable.
•4.Prior radiotherapy to the head and neck area that would result in overlap of radiation therapy fields.

发起方

Prince Aly Khan Hospital