NCT03649555已完成1 期
Reliability of [18F]-FTC-146 Brain Uptake in Healthy Controls
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 5
- 试验地点
- 1
- 主要终点
- Reliability under test retest conditions
研究概览
简要总结
The purpose of this study is to understand the reliability of [18F]-FTC-146 brain uptake in healthy controls.
详细描述
The purpose of this study is to understand the reliability of [18F]-FTC-146 brain uptake in healthy controls under test and retest conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •either gender and all ethno-racial categories
- •capacity to provide informed consent
- •Female participants are expected to use an effective method of birth control throughout the study
排除标准
- •Any current or lifetime psychiatric diagnosis
- •Current or past use of psychotropic medication
- •Pregnant or nursing females
- •Major medical or neurological problem
- •Presence of metal in the body that is contraindicated for MRI scans
研究组 & 干预措施
[18F]-FTC-146
Experimental
[18F]-FTC-146
干预措施: [18F]-FTC-146 (Drug)
结局指标
主要结局
Reliability under test retest conditions
时间窗: 1 week
Regional brain uptake of \[18F\]FTC-146 will be analyzed by kinetic modeling with metabolite-corrected arterial input functions to establish stability and reproducibility of \[18F\] FTC-146 VT in humans (n=6) under test and retest conditions.
次要结局
未报告次要终点
研究者
Carolyn Rodriguez
Assistant Professor
Stanford University
研究点 (1)
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