Further clinical study on evaluation of anti-cataract effect of Triphaladi Compound and Elaneer Kuzhambu in immature cataract w.s.r. Timira
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 1.Review of aetiopathogenesis of Timira as well as in modern literature and to establish a correlation with Cataract.
研究概览
简要总结
Senile Cataract is the most common type of Cataract which is age related, that contributes to as much as 75 % of blindness in India, generally affecting persons of age more than 50 years. While surgery remains the only accepted treatment of Cataract, Immature Cataract in many cases is not handled properly. Surgery, although an effective means of cure Cataract has not however eliminated the current problem leading to blindness due to many reasons.
-
Long waiting list
-
Cost of Surgery
-
Risk of Complications
-
Lack of Technical hand and Equipments
In such a scenario, a study on Immature Cataract management gains much importance and therefore this endeavour. Among many anti Cataract medicines Elaneer Kuzhambu is extensively used clinically in Kerala by local physicians, however, which has given good anti cataract effect in previous study.ref.
- Triphaladi compound- is a ayurvedic medicine prepared with 11 ingredients which are given below
Triphaladi Compound
| No |
Drug name
Botanical name
Part used
Part
|1.
Amalki
Emblica officinalis
Fruit
1
|2.
Haritaki
Terminalia chebula
Fruit
1
|3.
Bibhitaki
Terminalia bellerica
Fruit
1
|4.
Daruharidra
Berberis aristata
Bark
1
|5.
Haridra
Curcuma longa
Rhizome
1
|6.
Guduchi
Tinospora cordifolia
Stem
1
|7.
Gokshura
Trabulus terrestris
Panchang
1
|8.
Shunthi
Zingiber officinale
Rhizome
1
|9.
Punarnava
Boerhavia diffusa
Root
1
|10.
Yashtimadhu
Glycyrrhiza glabra
Root
1
|11.
Tulsi
Ocimum sanctum
Leaf
1
- Elaneer Kuzhambu- is again an ayurvedic medicine for eye. anjana is a group of medicines which are applied in eye with the help of a glass or metal rod. ingredients of elaneer kuzhambu is also an anjana and its ingredients are as follows as mentioned in Sahasrayogam an ancient ayurvedic book
Elaneer Kuzhambu
| No. |
Drug
Botanical name
Part used
Part
|1.
Daruharidra
Berberis aristata
Bark
1
|2.
Haritaki
Terminalia chebula
Fruit
1
|3.
Bibhitaki
Terminalia bellerica
Fruit
1
|4.
Amalaki
Emblica officinalis
Fruit
1
|5.
Yashtimadhu
Glycyrrhiza glabra
Root
1
|6.
Narikela
Coccus nucifera
jala
16
3. immature cataract w.s.r. timira-
timira is an ayurvedic group of diseases and immature catarct can be included in this
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 35.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Men and women 20 in each arm who meet the diagnostic standards of Immature Cataract
- •aged 35- 60 years of age are included in this study.
排除标准
- •Subjects who are suffering from-
- •congenital Cataract
- •mature and hyper mature Cataract
- •Diabetic Retinopathy
- •Macular degeneration
- •Retinitis pigmentosa
- •whose RBS and Blood Pressure are not within normal limits
- •who are under steroid treatment & or any kind of Immunosuppressive therapy or
- •under any Cataract inducing medication are excluded from this study.
结局指标
主要结局
1.Review of aetiopathogenesis of Timira as well as in modern literature and to establish a correlation with Cataract.
时间窗: 1. Conceptual Study- Till June 2014 | 2. Clinical Study- Till March 2015
2.To assess the efficacy of test drugs as anti-Cataract agents in the clinical trial.
时间窗: 1. Conceptual Study- Till June 2014 | 2. Clinical Study- Till March 2015
次要结局
- 1.To compile all the information related to the test drugs Elaneer kuzhambu anjana and Triphaladi yoga.(1. Conceptual Study- Till June 2014)