Role of Parasitic Infection in Inflammatory Bowel Disease and Irritable Bowel Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Detect the prevalence of parasite/s associated with Inflammatory bowel diseases (IBD) and Irritable bowel syndrome (IBS) in comparison with control subjects.
研究概览
简要总结
Role of parasitic infection in Inflammatory bowel disease and Irritable bowel The burden of the parasitic disease is in-direct relation with the health and nutritional status of the host, inducing not only parasite-specific immunity but also can modify the host's immune responses . Many parasites can imitate inflammatory bowel disorders and some studies showed that infection with parasites can improve disorders like IBD or moderate the symptoms of inflammatory bowel disorders . Even though, many studies have shown that gastrointestinal infection is an important risk factor for the development of IBS
详细描述
- Detect the prevalence of parasite/s associated with Inflammatory bowel diseases (IBD) and Irritable bowel syndrome (IBS) in comparison with control subjects.
- Evaluating the effect of the parasite on the course and prognosis of the diseases.
- Evaluating the effect of the antiparasitic drugs on the course and prognosis of the diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 17 Years 至 69 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of IBD will be confirmed using
- •standard clinical,
- •endoscopic,
- •radiographic and4 pathological criteria according to the Montreal classification of the extent and severity of IBD
- •Diagnosis of IBS will depend on Rome IV criteria
- •Recurrent abdominal pain on average at least 1 day/week in the last 3 months,
- •associated with two or more of the following criteria:
- •Related to defecation;
- •Associated with a change in the frequency of stool and/ or Associated with a change in the form (appearance) of stool.
排除标准
- •any patient who received antipiotic or antiparasitic drug within the past 4 weeks
结局指标
主要结局
Detect the prevalence of parasite/s associated with Inflammatory bowel diseases (IBD) and Irritable bowel syndrome (IBS) in comparison with control subjects.
时间窗: baseline
Detect the prevalence of parasite/s associated with Inflammatory bowel diseases (IBD) and Irritable bowel syndrome (IBS) in comparison with control subjects.by making stool analysis and clinical examination
次要结局
- measure the effect of the antiparasitic drugs on the course and prognosis of the diseases(baseline)
研究者
marina gamil shwqi
principle investigator
Assiut University