EUCTR2007-005274-31-IT进行中(未招募)不适用
Efficacy assessment of tetracycline in patients with progressive external ophthalmoplegia. - TETRA-PEO
AZIENDA OSPEDALIERA PISANA0 个研究点开始时间: 2008年10月9日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •a. PEO or PEO plus, confirmed by histopathologic reports (presence of ragged red fibres in muscular biopsy), biochemical reports (compromising of mitochondrial respiration) and molecular reports (deletions or mutations of mtDNA); b. Age from 18 years to 68 years; c. Negative pregnancy test in fertile women.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •a. Poor compliance with previous treatments; b. Patients that partecipate in other clinical trial; c. Patients with serious organ's diseases (cardiologic, neurologic, neoplastic, pneumologic and endocrinologic disease); d. Patients with history of sensitivity or intolerance of tetracycline and patients with concomitant diseases that contraindicate tetracycline administration (myasthenia gravis, systemic erythematus lupus, renal or hepatic diseases).
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