The effect of Tetrahydrocannabinol on ocular hemodynamics in healthy subjects - ONH Blood Flow THC

Medical University of Vienna, Department of Clinical Pharmacology0 个研究点目标入组 24 人开始时间: 2018年3月6日最近更新: 2019年2月28日

适应症

试验速览

暂无简介。

•Men and women aged between 18 and 35 years
•Normal ophthalmic findings
•Ametropia = 6 diopters
•Normal findings in the medical history and physical examination including ECG unless the investigator considers an abnormality to be clinically irrelevant
•Normal findings in the laboratory testing unless the investigator considers an abnormality to be clinically irrelevant
•Nonsmokers
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 24
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Regular use of medication, abuse of alcoholic beverages or drugs
•History of drug or alcohol abuse
•Psychiatric disorders in the medical history
•Risk for drug dependence as evaluated by a psychiatrist
•Participation in a clinical trial in the 3 weeks preceding the study
•Positive urine drug test at the screening examination or on the study days
•Positive alcohol breath test at the screening examination or on the study days
•Regular consumption of cannabis and inability to not consume cannabis during the study period
•Treatment in the previous 3 weeks with any drug (except intake of oral contraceptives)
•Symptoms of a clinically relevant illness in the 3 weeks before the first study day
•History or presence of gastrointestinal, liver or kidney disease, or other conditions known to interfere with distribution, metabolism or excretion of study drugs
•Blood donation during the previous 3 weeks
•Known hypersensitivity to any of the components of the IMP under investigation or other study medication
•History or family history of epilepsy
•Pregnant or breast-feeding women
•Women of childbearing potential (neither menopausal, nor hysterectomized, nor sterilized) not using effective contraception (oral contraceptives, intra-uterine device, contraceptive implant or condoms)

发起方

Medical University of Vienna, Department of Clinical Pharmacology