Efficacy Testing of Hibiscus Sabdariffa Extract and Collagen Products
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The change of skin wrinkles
研究概览
简要总结
To assess Hibiscus sabdariffa extract and collagen products on skin condition improvement
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged above 20 years old
排除标准
- •Subject who is not willing to participate in this study.
- •Patients with diseases of the skin, liver, kidney.
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
- •Constant drug use
- •Students who are currently taking courses taught by the principal investigator of this trial.
研究组 & 干预措施
Hibiscus sabdariffa extract and collagen products
干预措施: Hibiscus sabdariffa extract and collagen products (Dietary Supplement)
Placebo sachet
干预措施: Placebo sachet (Dietary Supplement)
结局指标
主要结局
The change of skin wrinkles
时间窗: Week 0, week 4, week 8
VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin elasticity
时间窗: Week 0, week 4, week 8
SoftPlus was utilized to measure skin elasticity. Units: arbitrary units
The change of skin moisture
时间窗: Week 0, week 4, week 8
Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin texture
时间窗: Week 0, week 4, week 8
VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin collagen density
时间窗: Week 0, week 4, week 8
DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units
次要结局
- The change of skin L* value(Week 0, week 4, week 8)
- The change of skin spots(Week 0, week 4, week 8)
- The change of skin melanin index(Week 0, week 4, week 8)
- The change of transepidermal water loss (TEWL)(Week 0, week 4, week 8)
- The change of skin pores(Week 0, week 4, week 8)