NCT00745329Unknown不适用
The Effect of Infliximab,Adalimumab, Azathioprines and 5-Aminosalicylate on Semen Quality in Men With Inflammatory Bowel Disease
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 100
研究概览
简要总结
Background: The treatment of inflammatory bowel diseases (IBD) is based mainly on 3 compounds: 1- 5 aminosalysilates . 2- immunomodulators (Azathioprines). 3- Biologic therapies (Infliximab, Adalimumab) . There are no established data in the literature whether these therapies effects sperm quality. Given that a large number of the patients are young men in the reproductive stage of their lives , It of importance to investigate these effect.
Aim: To investigate the effect of chronic treatment of any of the three therapy mentioned above, on sperm quality .
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male above the age of 18
- •Capable of giving informed consent
- •Diagnosed with IBD at least 3 months
- •Patients that are going to start a treatment with on of the following groups: 5ASA, Azathioprines, infliximab or ADAlimumab
- •Patients that are treated with therapies mentioned in article 4 for at least 3 months
排除标准
- •Male younger than 18
研究者
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