Validating a Clinical Decision Support Tool for Stratifying Stroke Risk in Patients Presenting With Dizziness to the Emergency Department
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 600
- 主要终点
- Number of participants with stroke
研究概览
简要总结
This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.
详细描述
This is a cross-sectional, hospital-based study, with no randomization procedure. Over a 21-month period, approximately 600 subjects will be enrolled. The study will assess the risk of stroke in each patient using a machine-learning model. To detect ischemic or hemorrhagic stroke, each patient will undergo a non-contrast brain magnetic resonance imaging study. The predictive performance of the machine-learning model will be evaluated in terms of accuracy, precision, recall, F1 score, and area under the receiver operating characteristics curve.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Presenting to the emergency department with dizziness or vertigo
- •Aged ≥ 20
- •Dizziness or vertigo lasting for at least 1 hour and < 7 days
- •Persistent dizziness or vertigo at the time of the examination at the emergency department
排除标准
- •Having 5 or more prior episodes similar in quality, intensity, and duration to the current symptoms, with at least one episode more than a year prior and one within the past year
- •Having frank stroke-like symptoms or signs, such as hemiparesis, facial asymmetry, dysarthria, dysphasia, ataxia, gaze palsy
- •Consciousness disturbance, Glasgow coma scale < 13
- •Severe dementia
- •Recent stroke within 3 months
- •Dizziness or vertigo thought to be the result of head injury, hypotension, medication/drug intoxication, hypoglycemia, electrolyte imbalance, anemia, hepatic encephalopathy, hydrocephalus, etc
- •Concomitant head or neck trauma
- •Severe degenerative cervical spondylosis
- •Having contraindications to magnetic resonance imaging examination
结局指标
主要结局
Number of participants with stroke
时间窗: Between 24 hours and 14 days after the emergency department visit
Number of participants with ischemic or hemorrhagic stroke confirmed by brain magnetic resonance imaging
次要结局
未报告次要终点