NL-OMON53203招募中不适用
Role of adrenaline in the inflammatory response in people with diabetes mellitus type 1, and healthy individuals - Adrenaline induced inflammation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •Ability to provide written informed consent Body-Mass Index: 19-30 kg/m2 Age >=16 years, <= 75 years Blood pressure: <140/90 mmHg Non-smoking Electrocardiogram not showing any serious arrythmia*s (PVC*s and PAC*s accepted)
排除标准
- •Any event of cardiovascular disease in the past 5 years (e.g. myocardial infarction, stroke, heart failure, symptomatic peripheral arterial disease) Pregnancy or breastfeeding or unwillingness to undertake birth control measures Epilepsy, Current treatment with Alpha or beta blockers ( doxazosin, propranolol) History of panic disorders History of Arrhythmias Use of immune-modifying drugs or antibiotics Use of tricyclic antidepressants or MAO inhibitors Use of statins (e.g. stop statins >2 weeks before performing blood sampling. Any infection with systemic symptoms in past 2 weeks Vaccination in the past 2 weeks Proliferative retinopathy Nephropathy with an estimated glomerular filtration rate (by MDRD) *60ml/min/1.73m2 Overt impaired hypoglycaemic awareness assed by the Clarke Questionnaire 4 or highe
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