ACTRN12617001099314终止未知
Genotype and Adeno-Associated Virus (AAV) Immune Status of Patients with Inherited Blood Diseases (Haemophilia A and B)
Department of Cell & Molecular Therapies, Royal Prince Alfred Hospital0 个研究点目标入组 15 人开始时间: 2017年7月28日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 终止
- 发起方
- 入组人数
- 15
研究概览
简要总结
This study planned to recruit 30 participants. However, recruitment had to cease due to a halt in testing at the central laboratory. A total of 16 participants were recruited but one participant was excluded as their sample was not analysed by the central laboratory. Seven participants had haemophilia A and eight participants had haemophilia B. Seven of the study participants did not have AAV neutralising antibodies.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- Male
入选标准
- •1. Male of 18 years or older.
- •2. Hereditary blood disease, including Haemophilia A or B.
- •3. Able to provide informed consent according to the guidelines of the Sydney Local Health District Ethics Review Committee.
排除标准
- •1. Subjects with a blood disease not due to a genetic mutation.
- •2. Subjects with less than 1-year life expectancy.
- •3. Investigator judgment that subject will be unable to comply with study endpoints.
研究者
相似试验
已完成
2 期
WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular ElectroporationLeukaemia (Acute)Leukaemia (Chronic)Leukaemia (Acute Myeloid)Leukaemia (Acute Lymphoblastic)Leukaemia (Acute Promyelocytic)NCT01334060University Hospital Southampton NHS Foundation Trust23
已完成
1 期
Safety of cell immunotherapy for refractory malignant tumor using natural killer cell-like effector cells (CA-MED-NK001) selectively amplified from autologous mononuclear cells in peripheral bloodall classes of malignant tumors, after treatment with (or not applicable for) standard therapies for cancersJPRN-UMIN000015733Center for Advanced Medical Innovation, Kyushu University10
已完成
不适用
Pilot study evaluating changes in the oral mucosa using optical coherence tomography as part of radio(chemo)therapy in patients with head and neck cancerC04C10Malignant neoplasm of floor of mouthMalignant neoplasm of oropharynxDRKS00015229niversitätsklinikum Carl Gustav Carus Dresden, Klinik und Poliklinik für Strahlentherapie und Radioonkologie1
已完成
不适用
Correlation analysis between pouchitis disease activity and measuring fecal concentration of calprotectipouchitisJPRN-UMIN000014915Hyogo College of Medicine15
已完成
不适用
Randomized trial of whey protein to prevent colorectal neoplasiacolorectal neoplasiaJPRN-UMIN000032746Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Katsushika Medical Center10