Pulsed Dye Laser for the Psoriatic Nail
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- NAPSI
研究概览
简要总结
The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.
详细描述
Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Psoriatic nail refractory to other topical and systemic treatment therapy
- •≧ 16 years old
排除标准
- •Patient with pregnancy
- •Patient with photo sensitivity
- •Patient with severe wound around finger nails or paronychia
- •Patient with hypersensitivity to Tazarotene cream
结局指标
主要结局
NAPSI
时间窗: 3rd and 6th months
global physician assessment
时间窗: 3rd and 6th months
次要结局
未报告次要终点
研究者
Ying-Yi Chiang
Attending Physician
Taipei Medical University WanFang Hospital