Improving outcome in subarachnoid hemorrhage with nadroparin

Amsterdam UMC Stichting0 个研究点目标入组 100 人开始时间: 2024年5月24日最近更新: 2024年8月21日

适应症

试验速览

暂无简介。

•SAH confirmed by CT or lumbar puncture with the causative aneurysm confirmed by CT-A and/or DSA, Coiling of the causative aneurysm within 72 hours of initial SAH, Informed consent before the first scheduled administration of the study medicine, Adult age (=18 years)

•Stent-assisted coiling, Use of anticoagulant or dual antiplatelet medication post-coiling for other reasons, Incomplete aneurysm occlusion/partial coiling, Intraparenchymal hemorrhage, Pregnancy, Contra-indications for LMWH: oPrevious history of history of heparin-induced thrombocytopenia o(Suspicion of) active arterial or venous bleeding oPrevious history of hemorrhagic diathesis due to coagulation disorders (with the ex-ception of disseminated intravascular coagulation) oSevere hypertension: uncontrolled hypertension with a MAP > 135mmHg oPrevious history of hypertensive or diabetic retinopathy oPrevious history of active infectious endocarditis oSevere renal impairment (creatinine clearance <30 mL / min), No proficiency of Dutch or English language, Proven and active COVID-19 infection

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