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临床试验/NCT01086176
NCT01086176已完成不适用

The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium

Maisonneuve-Rosemont Hospital1 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2010年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
22
试验地点
1
主要终点
The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%

研究概览

简要总结

The purpose of this study is to see how long does the effect of a post-tetanic facilitation last on subsequent train-of-four. The investigators hypothesis is that the effect last at least 30 minutes.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient having general anesthesia in dorsal decubitus with both arm available for at least an hour and a half

排除标准

  • Age >75 or <18
  • Neuromuscular disease
  • difficult laryngoscopy predicted
  • Allergy to rocuronium
  • Malignant hyperthermia
  • Full stomach
  • Drugs the influence neuromuscular blockers
  • Decision of the clinician to exclude his patient

结局指标

主要结局

The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%

次要结局

  • The difference at 30 minutes after the post-tetanic count on the T1% (of the calibrated T1) in both arms, we expect a difference of more than 10%
  • The difference of the slope of recuperation on TOF and T1% after a post-tetanic count vs the control arm that had no tetanic stimulation

研究者

申办方类型
Other

研究点 (1)

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