A Prospective Randomized Trial Comparing Treatment of Recurrent HCC With Repeat Hepatectomy,and Transcatheter Arterial Chemoembolization (TACE) With AFP Conversion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- overall survival
研究概览
简要总结
The purpose of this study is to compare the treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion.
详细描述
Though many HCC patients have been benefited from hepatectomy treatment, still the high recurrence rate after the hepatectomy led to limited effectiveness.
This is the first study in same case system on comparison of effectiveness among repeat hepatectomy, and TACE with AFP conversion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •via clinical diagnosis and confirm it is early recurrent liver cancer with AFP conversion, and not accept any anticancer treatment.
- •age:18-70years
- •better liver function (Child-Pugh，class A or B)
排除标准
- •reject to attend；
- •impossible to come to our hospital for physical examination regularly.
- •cancer epitome、seed focus、lymph node or distant metastasis
- •Blood clotting function hindrance;
- •serious heart、lung、kidney disease
研究组 & 干预措施
TACE
干预措施: Hepatectomy (Procedure)
hepatectomy
Comparison of Treatment of recurrent hepatocellular carcinoma with repeat hepatectomy,and transcatheter arterial chemoembolization (TACE) with AFP conversion
干预措施: TACE (Procedure)
结局指标
主要结局
overall survival
时间窗: 3 years
次要结局
未报告次要终点
研究者
ShenFeng
vice president of the Eastern Hepatobiliary Surgery Hospotal
Eastern Hepatobiliary Surgery Hospital