Development of Computer-Aid Diagnosis System for T1b Colorectal Cancer on Non-magnified Plain Endoscopic Images: A Multicenter Study - CAD for T1b CRC by Plain Images

At 90% cutoff for per-lesion score, the CADx system showed the highest specificity of 94.4% [95% confidence interval: 91.3-96.6], with 59.8% [48.3-70.4] sensitivity and 87.3% [83.7-90.4] accuracy. The area under the characteristic curve was 85.1% [79.9-90.4] for CADx, 88.2% [83.7-92.8] for expert 1, 85.9% [80.9-90.9] for expert 2, 77.0% [71.5-82.4] for trainee 1 (CADx vs. trainee 1: p=0.0076), and 66.2% [60.6-71.9] for trainee 2 (CADx vs. trainee 2: p<0.0001).