Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction Protocol
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- OSDI
研究概览
简要总结
The purpose of this study is to assess the sensation of ocular dry eye symptom after an intravitreal injection of anti-VEGF.
详细描述
The recrutement of the patient is done during the inclusion of the patient by the nurses of the ophtalmological service of clermont-ferrand and confirm by an ophtalmologist of the service.
A mesure of the OSDI is done before the injection, then at 1 day, on week by a phone call. Each of this mesures are done for the 2 other injections.
Before each of this injection, a clinical mesure is done by a lacrydiag: the atrophy of the meibomian glands, the non-invasive break-up time, interferometry, the heigh of the tear meniscum.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with exsudative age-related macular degeneration, diabetic macular edema or retinal vein occlusion
- •Patient with 3 ocular intravitreal injections of anti-VEGF in one eye
排除标准
- •pregnant or breastfeeding woman
- •intravitreal injection before the study
- •intravitreal injection in both eyes
- •allergy of betadine
- •guardianship patient
结局指标
主要结局
OSDI
时间窗: before the injection and at 1 day
Ocular Surface Disease Index: 12 questions treating of either the sensation, the visual impact and the environemental impact of the dry eye disease
次要结局
- HM(before each injection)
- AM(before each injection)
- NIBUT 2(before each injection)
- OSDI(before the injection and at 1 week)
- NIBUT 1(before each injection)
- Interferometry(before each injection)