Buccal Misoprostol Versus IV Oxytocin in Prevention of Postpartum Hemorrhage :a Randomized Controlled Study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 154
- 试验地点
- 1
- 主要终点
- mean blood loss
研究概览
简要总结
Cesarean delivery is defined as fetal birth through incisions in the abdominal wall and the uterine wall (hysterotomy). This definition does not include removal of the fetus from the abdominal cavity in the case of uterine rupture or in the case of an abdominal pregnancy
详细描述
patients and methods:
Type of Study
A prospective registered, double blinded, randomized controlled trial
Settings and localizations:
Operative list and emergency unit at Obstetrics and Gynecology Department, Women Health Hospital, Assiut university, Egypt
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •pregnant women
- •term pregnancy
- •singleton pregnancies
- •booked for elective cesarean section
排除标准
- •• Medical disorders involving the heart,liver,kidney or brain
- •Diabetes mellitus and hypertension
- •Blood disorders (e.g. coagulopathies , thrombocytopenia )
- •Patients requiring blood transfusion due to anemia
- •Risk factors for uterine atony e.g. macrosomia , polyhydramnios ,multiple pregnancies
- •Placenta previa or placental abruption
- •Previous major obstetric haemorrhage (>1000ml)in previous deliveries
- •Known fibroid or adenomyosis
- •Severe preeclampsia
- •Uterine anomalies
- •Women who received anticoagulant therapy
研究组 & 干预措施
study group
patients will receive buccal misoprostol
干预措施: Misoprostol (Drug)
control group
patients will receive intravenous oxytocin
干预措施: Oxytocin (Drug)
结局指标
主要结局
mean blood loss
时间窗: 1 hour
the amount of blood in towels and suction drain
次要结局
未报告次要终点
研究者
abo bakr mitwally
Principal investigator
Assiut University