Molecular Metastasis in Lymph Nodes is Associated With Survival of Patients With Stage I NSCLC
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 237
- 主要终点
- Correlation between driver gene mutation and survival prognosis in regional lymph nodes of early stage NSCLC
研究概览
简要总结
Analysis of driver gene variation in early stage non-small cell lung cancer
详细描述
Fluorescence quantitative polymerase chain reaction (PCR) was used to detect the variation of driver gene in regional lymph nodes of early stage non-small cell lung cancer (NSCLC), and to analyze the relationship between the variation and disease recurrence and survival prognosis. evaluate the effect of the variation of driving gene in lymph nodes of early stage NSCLC on prognosis, identify the high-risk factors that promote the recurrence and metastasis of early stage tumor. so as to improve the diagnosis and treatment path of lung cancer, provide important pathological basis for the clinical diagnosis and treatment of early stage non-small cell lung cancer, enable patients to receive more accurate treatment, and improve their survival prognosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Female or male, 18 years of age or older
- •Histologically or cytologically proven diagnosis of early stage NSCLC
- •The lesion was completely resected by radical surgery
- •Able to get tumor tissue sample
- •Complete information of clinicopathological , survival, recurrence and metastasis can be obtained through follow-up
排除标准
- •Combine with other tumor type
- •The investigator judges the situation that may affect the clinical search process and results
结局指标
主要结局
Correlation between driver gene mutation and survival prognosis in regional lymph nodes of early stage NSCLC
时间窗: 2019
Observe the correlation between driver gene mutation and survival prognosis in regional lymph nodes of early stage NSCLC
Correlation of Clinicopathological characteristics and driver gene mutation in regional lymph nodes of early stage NSCLC
时间窗: 2019
Analyze the correlation between driver gene mutation and clinicopathological features in regional lymph nodes of early stage NSCLC
Driver gene mutation frequency of early stage NSCLC
时间窗: 2019
Observe the driver gene mutation frequency in regional lymph nodes of early stage non-small cell lung cancer
次要结局
未报告次要终点
研究者
zjszlyyad@126.com
Director of pathology
Zhejiang Cancer Hospital