An open label randomized controlled clinical study to evaluate the effect of Karanja Kshara Lepa in KarniniYonivyapath visavis Cervical Erosion

Cervical Erosion or Cervical Ectopy, is characterized by the replacement of the squamous covering of the vaginal portion of the cervix with columnar epithelium, which remains contiguous with the lining of the endocervix1 . Cervial erosion or ectopy is the commonest lesion of the cervix. The prevelace rate of the erosionwith the parity capturing up to 17%-50% of the population2. The complications encountered by diathermy, cauterization, laser therapy, etc like local operations on the cervix causes menstrual disturbances, reactionary haemorrhages, cervical stenosis, sepsis, perforation of cervix, troublesome vaginal discharge and effect on subsequent pregnancy and child birth. The etimology and features of cervical erosion, it can be corelated to Karnini Yoni Vyapath. The symptoms include Kapha Dushti Lakshana like Shwetha Pichhila Srava, Kandu in Yoni3 . And the main treatment for Karnini Yoni Vyapath is mentioned as Sthanika Shodhana. Going through the Kshara Gunas i.e.Ushna Virya, Tikshna Guna, Vrana Shotha Pachaka, Sroto Shodhaka, Klinnata Shoshaka, Raktatisrava Stambhaka, Ropaka, Kathina Unnata Mamsadi Lekhaka4 . Comparing the line of treatment and the Kshara Gunas, it is observed that Kshara can be used in the treatment of cervical erosion. Few studies have been done previously done with different types of Kshaara in Karnini Yoni Vyapath. Karanja and Apamarga are the easily available drug , it is mentioned as Kshara Dravya’s according to Sushrutha and Vagbhata5,6 Karanja is mentioned as Yonirogahara according to Dhavantrari Nighantu7 . Yashtimadhu Taila has properties like Lekhana, Sodhana, Soshana, Stambhana, Sandhaniya, Ropana and Varnya, Vedanahara 8 . Keeping in view, the above-mentioned symptomatology and problems in treating them, there is a need for an alternative, safe and cost-effective remedy in Ayurvedic system. Hence the study “AN OPEN LABEL RANDOMIZED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFECT OF KARANJA KSHARA LEPA IN KARNINI YONIVYAPATH VIS-À-VIS CERVICAL EROSION” has been undertaken