Point of care ultrasound (POCUS) to detect diaphragmatic dysfunction in adult patients undergoing cervical spine surgery: A prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 135
- 试验地点
- 1
- 主要终点
- Number of patients diagnosed to have diaphragmatic dysfunction by point-of-care ultrasound preoperatively and at 72 hours after surgery
研究概览
简要总结
Introduction
Perioperative diaphragmatic dysfunction is often an incidental diagnosis. It is most commonly reported in high-level traumatic cervical spinal cord injury patients where the cervical spinal cord ischemia is the cause and also in cardiothoracic surgeries where the aetiology is phrenic nerve injury. It is not well studied in chronic cervical myelopathies and cranio-vertebral junction anomalies, where both these mechanisms can cause diaphragmatic dysfunction. Diaphragmatic ultrasound is a bedside, user-friendly and non-invasive method to detect diaphragmatic dysfunction routinely used in critical settings to predict weaning failure in critically ill patients. In our study, we plan to screen for diaphragmatic dysfunction in all adult patients undergoing cervical spine surgery in the perioperative period with the help of diaphragmatic ultrasound. We also plan to study its association with preoperative respiratory function, clinical myelopathy grading and postoperative respiratory complications.
Purpose
In our study, we plan to look at the prevalence of diaphragmatic dysfunction in the population undergoing cervical spine surgery in our hospital. Our primary objective is to identify those with diaphragmatic dysfunction in the perioperative period. Secondarily, we plan to examine the association between patients’ functional status, including their functional grading, bedside pulmonary function tests, and diaphragmatic dysfunction on the ultrasound. We hope to identify risk factors for postoperative respiratory complications in these patients. This study aims to identify patients at risk for diaphragmatic dysfunction and plan perioperative management and optimisation strategies in these patients.
Study design: Prospective, observational study.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)(—)
- 性别
- All
入选标准
- •Adults aged ≥18 years ii.
- •Cervical spine surgery: Laminectomy, corpectomy, discectomy, cervical spine fusion surgery for degenerative/traumatic indications, cervical spinal tumours (extradural, intradural extramedullary and intramedullary) iii.
- •Surgery for Craniovertebral junction anomalies iv.
- •Cervical spine trauma requiring surgery v.
- •ASA 1, 2 and 3.
排除标准
- •i.Patient refusal ii.
- •Patients on mechanical ventilation in the preoperative period.
- •Patients with low Glasgow coma scale (less than 8) and unable to obey commands.
- •Patients with preexisting medical conditions causing respiratory dysfunction, including but not limited to Guillain Barre syndrome, motor neuron diseases, and bulbar poliomyelitis.
- •v.Prior history of cardiothoracic surgery vi.
- •Recent upper abdominal surgery in the past six weeks vii.
- •ASA 4 and 5.
结局指标
主要结局
Number of patients diagnosed to have diaphragmatic dysfunction by point-of-care ultrasound preoperatively and at 72 hours after surgery
时间窗: preoperative baseline | and postoperative 72 hours
次要结局
- 1. Postoperative respiratory complications like respiratory failure, respiratory infections, respiratory distress, the requirement for non-invasive ventilation, reintubation, and prolonged mechanical ventilation within 30 days of discharge(2. Need for postoperative oxygen supplementation for more than 6 hrs.)
研究者
Dr.Bhargavi Vallabhaneni
Christian Medical college
