CTRI/2025/07/091683尚未招募不适用
Comparison of the effect of intrathecal Dexmedetomidine versus Buprenorphine as an adjuvant to Bupivacaine in spinal anaesthesia in lower limb orthopedic surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Onset and duration of sensory and motor blockade.
研究概览
简要总结
The supplementation of local anesthetics with adjuvants improve the efficacy of subarachnoid block.
This study was conducted to evaluate and compare the characteristics of subarachnoid block such as sensory and motor onset and duration , along with that the hemodynamic changes and adverse effects of intrathecal dexmedetomidine versus buprenorphine as an adjuvant with hyperbaric bupivacaine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anesthesiologists (ASA) grade 1 and 2 patients undergoing lower limb orthopedic surgeries.
排除标准
- •Study drug contraindicated.
- •contraindication of spinal anesthesia.
- •spinal deformity.
结局指标
主要结局
Onset and duration of sensory and motor blockade.
时间窗: 2 minute , 3 minute , 5 minute , 10 minute, 15 minute , 20 minute , 30 minute, 45 minute , 1 hour , 1.5 hour, 2 hour, 3 hour, 4 hour, 6 hour, 9 hour, 12 hour, 18 hour and 24 hours after spinal anesthesia.
次要结局
- Hemodynamic changes such as heart rate, systolic blood pressure, diastolic blood pressure , mean arterial pressure & need of post op analgesia.(Time since induction of anesthesia, intraoperatively at interval of 5 minutes for first 20 minutes followed by every 10 minutes for next 20 min followed by 30 minutes then at 2,4,6,9,12,24 hours.)
研究者
Dr Kachekar Aarti Suresh
Vilasrao Deshmukh Government Medical College, Latur
研究点 (1)
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