Developing diagnostic criteria for the differentiation between large vessel vasculitis and atherosclerosis using 18FDG-PET/CT - Vasculitis or Atherosclerosis on 18FDG-PET/CT / VAPC

Vrije Universiteit Medisch Centrum0 个研究点目标入组 60 人开始时间: 待定最近更新: 2024年4月23日

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•Patients with biopsy-proven giant cell arteritis with any type/degree of large-artery 18-FDG-uptake in the absence of clues pointing to severe atherosclerosis (history of cardiovascular disease or a >2-fold increased age-adjusted CVD risk. Patient scans will be retrieved from our database.;Group II:
•Patients with severe atherosclerosis affecting at least the thoracic and/or abdominal- iliacal aorta and any type/degree of large-artery 18-FDG uptake. Patients >50 years of age with manifest atherosclerotic disease will be selected from the vascular surgery outpatient clinic.

•Use of immunosuppressive drugs
•Known cancer
•Reluctance or inability to provide informed consent;Exclusion criteria for group II:
•ESR >30 mmHg and/or CRP >10 mg/l
•Myalgia in shoulder/pelvic regions (suggestive of PMR)
•History of vasculitis or other type of systemic auto-immune disease
•Use of immunosuppressive drugs
•Reluctance or inability to provide informed consent

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