Radiomics of Intra-abdominal and Subcutaneous Adipose Tissue Predict the Efficacy of Bariatric Surgery (RISABS)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 800
- 试验地点
- 1
- 主要终点
- Area under curve (AUC) of the T2DM remission prediction model after 1 year
研究概览
简要总结
Using radiomics of intra-abdominal and subcutaneous adipose tissue and clinical features to predict the weight loss efficacy and remission of type 2 diabetes mellitus after bariatric surgery.
详细描述
In this study, the investigator intend to collect abdominal CT from patients who are proposed to undergo bariatric surgery, to extract the radiomics of intra-abdominal fat and subcutaneous fat, and to establish a prediction model for predicting the efficacy of weight loss and remission of type 2 diabetes mellitus at 1 year, 3 years, and 5 years postoperatively, in conjunction with the clinical data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI>27.5kg/m2; Type 2 diabetes mellitus; Patients who will undergo bariatric surgery
排除标准
- •Patients without abdominal CT scan; Patients did not undergo sleeve gastrectomy or Roux-en-Y gastric bypass.
结局指标
主要结局
Area under curve (AUC) of the T2DM remission prediction model after 1 year
时间窗: 1 year
This metric shows the discriminatory ability of the radiomic model to predict the probability of remission of T2DM after 1 year.
Area under curve (AUC) of the weight loss prediction model after 1 year
时间窗: 1 year
This metric shows the discriminatory ability of the radiomic model to predict the probability of inadequate weight loss after 1 year.
次要结局
- Area under curve (AUC) of the weight regain model(5 years)
- Area under curve (AUC) of the weight loss prediction model after 3 years(3 years)
- Area under curve (AUC) of the T2DM relapse model(5 years)
- Area under curve (AUC) of the weight loss prediction model after 5 years(5 years)
- Area under curve (AUC) of the T2DM remission prediction model after 3 years(3 years)
- Area under curve (AUC) of the T2DM remission prediction model after 5 years(5 years)
研究者
Yuntao Nie
Principal Investigator
China-Japan Friendship Hospital