ISRCTN12353191已完成未知
A pilot randomized double-blinded single-dose provocation study on the effect of niacin on pulmonary arterial pressure
Georgetown University Institutional Review Board0 个研究点目标入组 49 人开始时间: 2015年4月23日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 49
研究概览
简要总结
2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26590128 results
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Over the age of 18
- •2. Display a tricuspid regurgitation jet velocity over 2.7 m/s on an inpatient echocardiogram during their current hospital stay
排除标准
- •1. Inability to provide written informed consent
- •2. Known pulmonary vascular disease
- •3. Known intolerance to niacin or current treatment with niacin
- •4. Current treatment with a non-steroidal anti-inflammatory drug (NSAID)
- •5. Known liver disease (AST/ALT > 3x the upper limit of normal)
- •6. Patients currently on ventilator support or using a bi-level positive airway pressure (BiPAP) device
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