Colorectal Cancer Screening in Xinxiang City
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25,000
- 试验地点
- 1
- 主要终点
- Sensitivity of colorectal cancer detection
研究概览
简要总结
The primary objective of this study is to evaluate the sensitivity of the fecal protein dual-index test reagent for the detection of colorectal cancer (CRC).
详细描述
The project uses fecal hemoglobin and transferrin dual-index combined with reagents that can be self-tested at home (referred to as fecal protein dual-index detection reagents), combined with colorectal cancer risk factor questionnaires, to carry out colorectal cancer screening in people of specific ages in the city, aiming to achieve early screening, early diagnosis and early treatment, and evaluate the effect of fecal protein dual-index detection reagents in early screening of colorectal cancer, so as to provide a scientific basis for optimizing the national screening program.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects aged 45-74 years at time of consent
- •Have not had gastrointestinal resection
排除标准
- •Previous history of colorectal cancer
- •Patients who have been confirmed to have other malignant neoplastic diseases of the digestive system
- •Patients with severe heart, brain, lung disease or liver and kidney dysfunction or insufficiency
- •Those with severe mental disorders and language communication disorders
- •History of contraindications to colonoscopy
- •Pregnant women
结局指标
主要结局
Sensitivity of colorectal cancer detection
时间窗: 180 days
Sensitivity of colorectal cancer detection
Specificity of advanced neoplasia detection
时间窗: 180 days
Specificity of advanced neoplasia detection
次要结局
- Positive predictive value of colorectal cancer detection(180 days)
- Negative predictive value of colorectal cancer detection(180 days)
- Sensitivity and specificity of advanced adenoma detection(180 days)