Effects of a home-based versus hospital-based outpatient pulmonary rehabilitation program in patients with chronic obstructive pulmonary disease (COPD): a multicentre, randomised trial

niversity Laval (Canada)0 个研究点目标入组 240 人开始时间: 2005年9月26日最近更新: 2019年2月11日

适应症

试验速览

•1. Subject is able to ambulate. Defined as a six-minute walking distance (6MWD) greater than 110 metres.
•2. Subject is diagnosed with COPD
•3. 40 years old and older, either sex
•4. Currently or previously smoking with a smoking history of at least 10 pack-years
•5. Forced expiratory volume in one second (FEV1) after the use of a bronchodilator between 25 and 70% of the predicted normal value, and FEV1 to forced vital capacity (FVC) ratio less than 70%
•6. Subject has a stable COPD condition defined as no COPD exacerbation or no changes in dyspnoea, volume or colour of sputum in the previous 4 weeks
•7. No previous diagnosis of:
•7.1. Asthma
•7.2. Left heart congestive heart failure (either radiographic evidence of pulmonary congestion, echocardiographic or ventriculographic evidence of a reduced ventricular ejection fraction)
•7.3. Terminal disease, dementia or uncontrolled psychiatric illness
•8. No participation to a respiratory rehabilitation program in the past year and not staying or planning to stay in a long-term care facility
•9. Subject understands and is able to read, write French or English

•The need for supplemental oxygen at rest or during exercise will not be an exclusion criterion

发起方

niversity Laval (Canada)