Intrapleural streptokinase adjunct to conventional treatment vs conventional treatment in paediatric empyema-An open labelled randomized control trial.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
This randomized open label controlled trial aims to evaluate the efficacy and safety of intrapleural streptokinase as an adjunct to conventional management in children with empyema . Participants aged 2 - 18 years with confirmed diagnosis of empyema will be randomized into two groups : one receiving conventional treatment alone while the other receiving intrapleural streptokinase in addition to conventional treatment . The primary outcome will be improved in clinical condition and radiological resolution , while secondary outcomes will include duration of hospital stay , need for surgical intervention and adverse effects . The study will be conducted in department of paediatrics at kalawati saran children’s hospital.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 2.00 Year(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with definitive diagnosis of empyema with visible puson diagnostic pleural tap and/or septations /loculations on ultrasound of chest.
排除标准
- •Any history of coagulopathy b.
- •Confirmed case of pneumothorax or bronchopleural fistula c.
- •Any history of head trauma in preceeding 2 weeks .
- •Any history of recent major surgery .
研究者
Shubham Rastogi
Lady hardinge medical college