Evaluation of Perioperative Celecoxib for Hip Arthroscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 98
- 主要终点
- Total Narcotic Consumption in the Post Anesthesia Care Unit (PACU)
研究概览
简要总结
Celecoxib is commonly used for perioperative pain control for certain orthopaedic procedures. It has been shown to be successful in assisting in pain control for knee arthroscopy. It has not previously been studied in hip arthroscopy. This is a double blinded randomized controlled trial to determine the efficacy of celecoxib in perioperative pain control for hip arthroscopy.
详细描述
This study examines the efficacy of perioperative dose of celecoxib in pain management after hip arthroscopy. Perioperative administration of celecoxib has been shown to improve pain control after knee arthroscopy, but this has not yet been studied in the hip. In this study, patients are randomized to receive either 400mg celecoxib or placebo 1 hour prior to undergoing hip arthroscopy surgery. Postoperatively, patients are monitored for pain on the VAS scale, narcotic use, and meeting discharge criteria. The study will enroll 100 patients. Patients are approached for informed consent on the day of surgery. Pain scores, narcotic use, and time to discharge in the celecoxib group are compared to the placebo group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who are undergoing a hip arthroscopy procedure at Northwestern Memorial Hospital with Dr. Michael Terry.
排除标准
- •Pregnant women and any patient under the age of 18 years.
研究组 & 干预措施
Intervention
Received 400mg celecoxib prior to surgery
干预措施: Celecoxib (Drug)
Placebo
Received placebo pill prior to surgery
干预措施: placebo (Drug)
结局指标
主要结局
Total Narcotic Consumption in the Post Anesthesia Care Unit (PACU)
时间窗: duration of PACU stay,immediate post op period up to a maximum of 4 hours postoperatively
Monitored consumption of narcotic medications following surgery, measured in morphine equivalents
Visual Analog Score for Pain (VAS) in the Immediate Post Operative Period
时间窗: Pre operative on day of surgery, immediately following OR close, 1 hr post operatively, 2 hrs post operatively
The pain VAS is a uni dimensional measure of pain intensity. It is a continuous scale comprised of a 0-10 pain rating. A score of 0 indicates no pain while a score of 10 would indicate extreme pain.
Time to Discharge Following Surgery
时间窗: time from OR to discharge, up to a maximum of 6 hours postoperatively
Total time to discharge from OR close following surgery, measured in minutes
次要结局
未报告次要终点
研究者
Michael Terry
Associate Professor
Northwestern University