Effect of Sensory Electrical Stimulation on Resting Tremors in Patients with Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- triaxial gyrosensor (accelerator)
研究概览
简要总结
Parkinson's disease is one of the most prevalent motor disorders in the world . The disease is progressive and has no known treatment. In addition to a number of psychological and autonomic issues, the disease also cause movement abnormalities which are the most challenging problem because management is still limited by medication or traditional physiotherapy the most effective way to treat symptoms is through an interprofessional new modalities as sensory stimulation , this study will be the first of its type to measure the effect of sensory stimulation on static tremors. Also, this study is the first of its type to make a continues treatment protocol for patient with static tremors.
SO the purpose of these study will To investigate the effect of sensory electrical stimulation on resting tremors in Parkinson's patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 45 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 45 and 60
- •Diagnosed with idiopathic Parkinson's disease with Magnetic resonance imaging of the brain
- •All the patients will have mild to moderate symptoms based on (the Unified Parkinson's Disease Rating Scale UPDRS) ≥ 3
- •Static tremors have been present at the hand and wrist
- •Absence of other disorders that cause similar symptoms like dystonia
排除标准
- •History of hand trauma causes stiffness
- •Presence of other neurological problems interferes with diagnosis as hemiplegic stroke
- •Secondary parkinsonism (drug-induced or vascular ) which has very low tremor magnitude which can not be detected The patient has a severe visual problem that does not allow following the instructions.
- •The patient educational level does not allow for following the instructions.
结局指标
主要结局
triaxial gyrosensor (accelerator)
时间窗: 3 weeks
Three-dimensional angular motion will measured at the index finger of the more affected hand, by using triaxial gyrosensor (STM32L151, STMicroelectronics, ). The gyrosensor will embedded in an elastic band and attached on the dorsum of proximal phalanx
Fahn-tolosa- marin clinical rating scale
时间窗: 3 weeks
Fahn_tolosa_marin clinical rating scale( FTM) is avalid scale for asses hand tremor, it consist of two items related to the hand , 1_trmors 2_hand writing The score is form 0 to 4 , 0 mean no tremors , 4 means severe tremors
次要结局
未报告次要终点
研究者
Mohamed Yassen
Principal Investigator
Cairo University