NCT00653809已完成不适用
Elucidating the Role of Nitric Oxide and Endothelin-1 Activation in Endothelial Cells Co-cultured With Placental Explants From African-american and Caucasian High Risk Pregnancies
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Nitric oxide and Endothelin-1 levels
研究概览
简要总结
The goal of this study is to examine the activation of markers of endothelial and cardiovascular dysfunctions, from women with high-risk pregnancies. Information from this study will hopefully provide enough information to determine a link between race, the advent of high risk pregnancies and cardiovascular markers. With this information it might be possible to intervene with approved pharmacological treatments.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •African-american or Caucasian
- •Between ages of 18 - 40 years of age
排除标准
- •Presence of a disease or condition which is not preeclampsia
- •Drug or alcohol abuse during pregnancy
结局指标
主要结局
Nitric oxide and Endothelin-1 levels
时间窗: 48 hours after tissue collection
次要结局
- Nitric oxide isoforms and Endothelin-1 receptor activation based on primary outcome(within 6 months from tissue collection)
研究者
Kedra Wallace
Postdoc Research Fellow
University of Mississippi Medical Center
研究点 (1)
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