Early Nutrition and Neurological Development of Very Preterm Infants
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 206
- 试验地点
- 1
- 主要终点
- Neurological development
研究概览
简要总结
The main goal of this study is to determine, in preterm infants born with a GA < 32 weeks, the association between:
- the quantity of mother's milk and duration and breastfeeding
- the intake of polyunsaturated fatty acids and iron during hospitalizations
详细描述
The main hypothesis of this study is that the intake of lipid during hospitalization in neonatology department is associated with neurological development of preterm infants born with a GA < 32 weeks. The other hypotheses are that iron intake and the duration of breastfeeding are also associated with the development of preterm infants.
In the previous study EPINUTRI (NCT01486173), the development of infants was evaluated until the age of 1 year. EPINUTRI_3 is the follow-up of EPINUTRI until the age of 3 years.
The aim of EPINUTRI_3 study is to determine the association between lipid intake during hospitalization in neonatology department of preterm infants born with a GA < 32 weeks.
The secondary objective is :
- to evaluate the association between these factors and communication, developmental and social-emotional delays with the test " Ages and Stages questionnaire " (ASQ) at 3 years of age.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 3 Years 至 3 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Premature infants previously included in EPINUTRI study
- •Non opposition of the parents for the collection of clinical and nutritional data
排除标准
- •Refusal of the parents to collect clinical and nutritional data
结局指标
主要结局
Neurological development
时间窗: At 3 years of age
Age and Stages Questionnaire
次要结局
未报告次要终点